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Two police officers were injured after responding to a shooting at a house in Delaware County, Pennsylvania, near Philadelphia, a county law enforcement source told CNN. Brynn Gingras reports.
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Grandmother says son fired gun and set house near Philadelphia afire. Now relatives presumed dead as wounded officers recover
Originally Published: 07 FEB 24 16:39 ET
Updated: 09 FEB 24 09:51 ET
By Danny Freeman, John Miller and Celina Tebor, CNN
(CNN) — A grandmother has identified her son as the man who fired gunshots and set their Philadelphia-area house on fire this week in an episode believed to have left several relatives dead in the home as two officers were wounded by gunfire.
The woman on Wednesday heard her 43-year-old son, Canh Le, arguing with and telling his 13-year-old niece he was going to get a gun, Chin Le told CNN affiliate WPVI on Thursday.
Then, Le and her husband left the East Lansdowne house, and her husband called 911, she told WPVI.
Three adults and three children now are feared dead, Delaware County District Attorney Jack Stollsteimer said Thursday. Canh Le, along with Chin Le’s other son, Xuong Le, and his wife, Britni Le, are believed to have died, along with their children: NaKayla, 13, NaTalya, 17, and Xavier, 10, the grandmother told WPVI.
Officials had “reason to believe” the person who shot at the officers responding to a report a child had been shot at the home is among those in the home unaccounted for, Stollsteimer said in a Wednesday news conference and an interview with CNN affiliate KYW-TV. Police have not publicly identified Canh Le as the shooter.
Authorities Thursday recovered a torso and a rifle from the “unstable” home as detectives methodically combed the crime scene with excavation experts and a drone, the district attorney said. Nobody had been left alive inside, he said.
The recovery process may take “hours” or even “days,” Stollsteimer said Thursday. “Unfortunately, I’m very confident that we’re going to find at least one body in there, and I think we’re going to find many more, several more.”
“These people’s bodies have been destroyed by fire, so we may have to resort to dental records and other means to try and determine who’s who when we do find more bodies – assuming we do,” Stollsteimer said.
Authorities had been working to nail down “whether or not an 11-year-old girl was or was not shot,” as well as who shot the officers, Stollsteimer said Wednesday. Also among the lingering questions is how and when the fire started – and who started it.
A chaotic scene unfolded in and around the home Wednesday as flames swallowed most of the structure, leaving nothing but a charred shell that released massive black smoke plumes, footage from CNN affiliate WPVI shows.
With the fire still raging, an armored vehicle at one point rammed the house, WPVI footage shows.
“I heard a lot of gunshots … and I just (saw) cops running from everywhere,” one neighbor told WPVI, adding they heard authorities yelling about an “active shooter.”
The family had lived in the house for at least five years, a neighbor told CNN.
Responding officers ‘met by gunfire’
Earlier Wednesday, a person had been barricaded in the house, a Delaware County law enforcement source told CNN.
Authorities then got a 911 call just before 3:50 p.m. Wednesday reporting “an 11-year-old girl had been shot” at the home in a borough a few miles west of downtown Philadelphia, Stollsteimer said at the news conference.
Someone claiming to be a child apparently called police and said they had been shot, another source briefed on the situation told CNN, adding it was unclear whether a child had actually been shot.
Officers from three agencies responded and were “immediately met by gunfire,” Stollsteimer said. Two officers were struck and “dragged out of danger” by colleagues, he said.
Officer David Schiazza, 54, of the Lansdowne Police Department, suffered a gunshot wound to his leg, Stollsteimer said; he was released Thursday afternoon from a Philadelphia hospital. Officer John Meehan, 44, of the East Lansdowne Police Department, suffered a gunshot wound to his left arm that required a lengthy surgery, he said; he was expected to be released by Friday. Both are 22-year veterans with their respective departments, he said.
After officers responded, the house was set ablaze, Stollsteimer said. The block was emptied of people and the fire brought mostly under control, though it still smoldered Wednesday night, Stollsteimer said at that time.
“There’s nobody else in danger,” he said. “We’re not going to make entry into that house until we know that the fire’s under control and that it’s safe for those officers to go in there … We don’t want another single officer hurt tonight in Delaware County.”
The William Penn School District is providing counselors to support students and staff, it said in a statement.
“This is a time when we need to be there for each other and to provide reassurance for our students, as it is impossible to make sense of what occurred,” the district said.
This story has been updated with additional information.
CNN’s Alisha Ebrahimji, Amy Simonson, Yan Kaner, Christina Maxouris and Kristina Sgueglia contributed to this report.
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Active shooter incident at home near Philadelphia
Embargo: Philadelphia, PA Police on the scene of a possible active shooter situation in East Lansdowne, Pennsylvania, on February 7.
KYW
07 Feb 24
Originally Published: 09 FEB 24 09:14 ET
Updated: 09 FEB 24 09:51 ET
By Elisabeth Buchwald, CNN
New York (CNN) — Last year, the Federal Reserve was caught off guard when the Bureau of Labor Statistics released revised Consumer Price Index figures showing inflation rose in December 2022 and did not fall as previously thought.
That left Fed officials bracing for the latest batch of revised CPI data, released Friday morning, which some feared could take away the inflation progress they observed last year.
That wasn’t the case though. Instead, officials got some good news: December’s monthly inflation wasn’t as bad as initially reported, according to newly revised figures from the BLS.
The new adjustments indicate prices increased by 0.2% in December from the prior month, compared to the initial estimate of 0.3%.
And for other months last year, initial data was either unchanged or revised by no more than one-tenth of a percentage point up or down.
The adjustments take into account recalculations of seasonal adjustment factors. However, this doesn’t impact the annual inflation rate the BLS reported, which remains at 3.4%. That’s a significant improvement from the end of 2022, when prices were increasing by 6.5% on an annualized basis.
Recent data revisions have complicated the Fed’s monetary policy decisions
Fed officials have been complaining about data revisions to key economic reports lately.
“We have to make decisions in real time,” Fed Governor Christopher Waller said late last year. “Whatever data is released, that’s the data I have to use. The problem with data is it gets revised.”
That wouldn’t necessarily be so much of an issue if the revisions, which can come months after initial reports are released, were relatively small. However, many revisions over the past few years have been game-changers.
Some of the biggest revisions came from the BLS’ monthly jobs report where often the initial number of jobs added is vastly different from the final revised figures.
That matters a lot for central bankers as they aim to bring inflation back down to their 2% annual target while limiting job losses. So if, for instance, at first it looks like job gains slowed a lot in one month, they could give more consideration to cutting rates sooner. But if revised data indicates that job gains didn’t actually slow that much in a month, cutting rates could move the inflation rate further from their target.
That’s partially why Waller said last month he would be paying close attention to Friday’s revised CPI data since it could potentially change “the picture on inflation.”
His comments heightened investors’ interest in the data, Kieran Clancy, senior US economist at Pantheon Macroeconomics, said in a note on Friday. “But he merely was covering all the bases with regards to inflation risks,” Clancy added, noting that “he likely was surprised by the scale of attention his comments received.”
“In short, these revisions to the seasonals are a damp squib,” he said.
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US inflation rates
**This image is for use with this specific article only** The annual inflation rate is still 3.4%, according to December’s Consumer Price Index report.
Frederic J. Brown/AFP/Getty Images
09 Feb 24
Originally Published: 09 FEB 24 09:54 ET
By Katie Hunt, CNN
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(CNN) — Why women are at greater risk of autoimmune disease such as multiple sclerosis, lupus and rheumatoid arthritis is a long-standing medical mystery, and a team of researchers at Stanford University may now be a step closer to unraveling it.
How the female body handles its extra X chromosome (the male body has just one plus a Y chromosome) might be a factor that helps explain why women are more susceptible to these types of disorders, a new study has suggested. The predominantly chronic conditions involve an off-kilter immune system attacking its own cells and tissues.
While the research involving experiments on mice is preliminary, the observation, after further study, may help inform new treatments and ways to diagnose the diseases, said Dr. Howard Chang, seniorauthor of the paper published in the journal Cell on February 1.
Chang, a professor of dermatology and genetics at Stanford School of Medicine who led the research, became interested in the topic because symptoms of some autoimmune disorders such as lupus and scleroderma manifest in the skin as rashes.
“Many of these diseases that show up in our clinics, especially the immune-related diseases, show this really striking female bias. And so I’ve always wondered about that from my own clinical practice,” he said.
There are more than 80 autoimmune diseases, affecting around 24 million people in the United States. The disorders occur when a person’s immune system gets confused and starts responding as if it’s being attacked by an infection when there is none, explained Montserrat Anguera, an associate professor in the department of biomedical sciences at the University of Pennsylvania School of Veterinary Medicine.
“The same sort of players that are acting in response to a virus or bacteria (are the ones) thatare acting in immune disease but in autoimmune disease the ‘infection’ isn’t being cleared, it’s persisting and with persistence, it’s getting magnified and it’s causing damage to tissues, depending on the autoimmune disease,” Anguera, who wasn’t involved in the research, explained. “Some of them affect the whole body and other ones are localized to a particular organ.”
Other researchers had focused on the disorders’ “female bias” by analyzing sex hormones or chromosome counts. Chang instead zoned in on the role played by a molecule called Xist (pronounced exist) that is not present in male cells.
Testing the ‘significant role’ of Xist
The Xist molecule’s main job is to deactivate the second female X chromosome in embryos, ensuring that the body’s cells don’t get a potentially toxic double whammy of the chromosome’s protein-coding genes.
“Xist is a very long RNA, 17,000 nucleotides long, or letters, and it associates with approximately almost 100 proteins,” Chang said. Xist molecules work with those proteins to shut down gene expression in the second X chromosome.
While studying for exams to renew his medical license just under a decade ago, Chang made a connection. He noticed that many of the proteins Xist works with to bind to and silence the X chromosome had a connection to skin-related autoimmune disorders: Patients with these conditions had autoantibodies that mistakenly attacked those normal proteins.
Chang wondered whether the clumps of protein molecules that arise when Xist connects with the X chromosome were a trigger for autoimmune disease.
To investigate, Chang decided to study how Xist, only produced naturally by female cells, would function if it were in male mice — a feat made possible by genetic engineering. This, he said, would be a first step in eliminating possible competing explanations for female susceptibility to autoimmune disease such as sex hormones or rogue proteins made by a second X chromosome that wasn’t fully turned off.
When male mice that had been modified to have a gene producing Xist were injected with a chemical irritant that mimicked lupus, the team found that male mice developed the hallmarks of autoimmunity — autoantibodies— at a rate approaching female mice, showing that the proteins that bind to Xist can provoke an immune response. The experiments weren’t designed to show whether Xist or the related proteins cause autoimmune disease in the animals.
Chang and his coauthors also analyzed samples of blood serum from humans with lupus, dermatomyositis and systemic sclerosis and compared them with samples from people without autoimmune disease. The samples from patients with autoimmune disease produced higher levels of autoantibodies in reaction to proteins associated with Xist, the researchers found.
Altogether, the data pointed to a “significant role” for Xist as a driver for autoimmunity that might explain why autoimmune disease skews female, according to the study.
A piece of the autoimmune puzzle
The study showed that the machinery of the inactive X chromosome was important and might be playing a role in the female bias in autoimmune disease, Montserrat said.
She added, however, that the latest finding was potentially just one piece in a very big puzzle — a “coral reef” in a big ocean. It’s not clear, she said, whether the proteins associated with Xist are really causing disease. Plus, environmental factors play a big role in autoimmune disease.
“It’s not just an individual’s genetics … there’s a whole other aspect which is interactions with the environment,” Anguera said. “So these are diet, microbiome, and then behaviors like smoking.”
READ MORE: Lab rats are overwhelmingly male, and that’s a problem
Autoimmune diseases are difficult to detect and often take years to diagnose. Ultimately, Chang said he hopes the findings could speed up that process.
“I think there’s a potential to pursue and explore the diagnostic potential (of Xist and if it) can better help somebody decide whether they have this or that kind of autoimmune disease,” Chang said. “The second area where we’re very interested in is therapeutics. Now that we know that Xist seems to be an important driver, how can you stop this process?”
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Karotype chromosomes
**This image is for use with this specific article only** Humans have 23 pairs of chromosomes. At bottom right are the pair of sex chromosomes XY or XX that determines sex.
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09 Feb 24
Description:From cheese to pepperoni, pizza is always a popular pick.
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Description:The bill would make selling and distributing detergent pods and certain laundry sheets illegal because of microplastics.
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Originally Published: 10 OCT 23 17:01 ET
Updated: 08 FEB 24 11:44 ET
By CNN Impact Your World
(CNN) — As deadly fighting between Israel and Hamas continues, so too does a dire humanitarian crisis in the area.
At least 1,200 people have been killed in Israel and, according to the Hamas-controlled Ministry of Health in Gaza, more than 27,000 people have been killed in Gaza after Hamas launched unprecedented attacks on Israel October 7. Subsequent airstrikes have overwhelmed local hospitals and internally displaced an estimated one million people in Gaza, one of the most densely populated areas on Earth.
The International Committee of the Red Cross (ICRC) is calling for the protection of aid workers, civilians, and critical infrastructure. Calling the situation “horrific,” Doctors Without Borders/Médecins Sans Frontières (MSF) is urging restraint after medical facilities have been destroyed in the fighting.
Impact Your World has gathered a list of vetted organizations that are on the ground responding. You can support their work by clicking HERE or using the form below.
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How to help humanitarian efforts in Israel and Gaza
Embargo: NONE As deadly fighting between Israel and Hamas continues, so too does a dire humanitarian crisis in the area.
CNN
18 Dec 23
According to Christie’s, the Fab Four were at the Tokyo Hilton when they were presented with a set of art materials. The group placed chairs around a table and worked on the painting in between concerts in Japan.
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With tax season officially open, CBS News Business Analyst Jill Schlesinger has what you need to know to start the process of preparing your return
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Originally Published: 08 FEB 24 11:24 ET
By Brian Fung, CNN
Washington (CNN) — The Federal Communications Commission said Thursday it is immediately outlawing scam robocalls featuring fake, artificial intelligence-created voices, cracking down on so-called “deepfake” technology that experts say could undermine election security or supercharge fraud.
The unanimous FCC vote extends anti-robocall rules to cover AI deepfake calls by recognizing those voices as “artificial” under a federal law governing telemarketing and robocalling.
The FCC’s move gives state attorneys general more legal tools to pursue illegal robocallers that use AI-generated voices to impersonate celebrities, politicians and close family members, the FCC said.
“Bad actors are using AI-generated voices in unsolicited robocalls to extort vulnerable family members, imitate celebrities, and misinform voters,” said FCC Chairwoman Jessica Rosenworcel in a statement. “We’re putting the fraudsters behind these robocalls on notice.”
The decision to interpret the Telephone Consumer Protection Act more broadly to include AI-generated voices comes weeks after a fake robocall that impersonated President Joe Biden targeted thousands of New Hampshire voters and urged them not to participate in the state’s primary.
Authorities said this week they had linked those fake calls to a Texas man and two companies in an ongoing investigation that could lead to civil and criminal penalties.
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Phone user
**This image is for use with this specific article only** FCC votes to outlaw scam robocalls that use AI-generated voices
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08 Feb 24